chronic inflammatory demyelinating polyradiculoneuropathy: A slowly progressive autoimmune demyelinating disease of peripheral nerves and nerve roots. Clinical manifestations include weakness and sensory loss in the extremities and enlargement of peripheral nerves. The course may be relapsing-remitting or demonstrate a step-wise progression. Protein is usually elevated in the spinal fluid and cranial nerves are typically spared. GUILLAIN-BARRE SYNDROME features a relatively rapid progression of disease which distinguishes it from this condition. (Adams et al., Principles of Neurology, 6th ed, p1337)
Other and unspecified polyneuropathies, also in other diseases
DOID EFO Endpoint Browser PheWeb
G6_POLYOTHUNS
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditionsNone |
429209 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
6242 |
4. Check minimum number of eventsNone |
6242 |
5. Include endpointsNone |
6242 |
6. Filter based on genotype QC (FinnGen only) |
6027 |
Control definitions (FinnGen only)
Control exclude
G6_POLYNEU
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Other and unspecified polyneuropathies, also in other diseases
based on the number of shared cases.
Broader endpoints:
- Polyneuropathies and other disorders of the peripheral nervous system
- Neurological diseases
- Neurological diseases
- Any event in hilmo or specialist outpatient
Narrower endpoints:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 49661 | 18926 | 30281 |
| Only index persons | 42397 | 16632 | 25765 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.73 | 0.54 | 0.85 |
| Only index persons | 0.84 | 0.61 | 0.98 |
| Median age at first event (years) | |||
| Whole population | 65.26 | 66.69 | 64.36 |
| Only index persons | 64.82 | 65.99 | 64.06 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 6027 | 2306 | 3721 |
| Unadjusted period prevalence (%) | 1.65 | 1.00 | 2.05 |
| Median age at first event (years) | 63.43 | 61.16 | 64.84 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: G6_POLYOTHUNS – Other and unspecified polyneuropathies, also in other diseases
GWS hits: 2
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