type I diabetes mellitus: A chronic condition characterized by minimal or absent production of insulin by the pancreas.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditionsNone |
429209 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
9780 |
6. Filter based on genotype QC (FinnGen only) |
9507 |
Control definitions (FinnGen only)
Control exclude
DIABETES_FG
Extra metadata
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Type 1 diabetes, wide definition
based on the number of shared cases.
Broader endpoints:
- Diabetes mellitus
- Endocrine, nutritional and metabolic diseases
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Narrower endpoints:
Case counts by codes
↥FinnGen case counts by registry codes:
No data for upset plot.
No data for upset table.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 66380 | 28645 | 37272 |
| Only index persons | 56753 | 24640 | 32113 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.94 | 0.82 | 1.04 |
| Only index persons | 1.09 | 0.91 | 1.23 |
| Median age at first event (years) | |||
| Whole population | 30.82 | 30.62 | 30.69 |
| Only index persons | 28.59 | 28.25 | 28.85 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 9507 | 4577 | 4930 |
| Unadjusted period prevalence (%) | 2.36 | 1.99 | 2.71 |
| Median age at first event (years) | 23.43 | 18.31 | 28.19 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: T1D_WIDE – Type 1 diabetes, wide definition
GWS hits: 48
Loading Relationships table