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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Type 1 diabetes, strict definition, subgroup 1

T1D_STRICT1

type I diabetes mellitus: A chronic condition characterized by minimal or absent production of insulin by the pancreas.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

  • not E4_DM2
  • and not PANCREATITIS
  • and KELA_DIAB_INSUL
  • and INSULIN_SHORTFAST
  • and INSULIN_INTER_AND_LONG
3881

3. Check pre-conditions, main-only, mode, registry filters

Pre-conditions: EVENT_AGE<40

Registry filters:

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

3443

6. Filter based on genotype QC (FinnGen only)

3357

Control definitions (FinnGen only)

Control exclude DIABETES_FG
Control conditions not E4_DM2
and not PANCREATITIS
and not KELA_DIAB_INSUL
and not INSULIN_SHORTFAST
and not INSULIN_INTER_AND_LONG

Extra metadata

First used in FinnGen datafreeze DF9

Case counts by codes

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 3357 1698 1659
Unadjusted period prevalence (%) 0.82 0.74 0.91
Median age at first event (years) 12.73 12.16 13.31

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: T1D_STRICT1 – Type 1 diabetes, strict definition, subgroup 1

GWS hits: -

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