Type1 diabetes, definitions combined, early onset

T1D_EARLY

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Pre-conditions: EVENT_AGE < 20

Registry filters:

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

2899

6. Filter based on genotype QC (FinnGen only)

2832

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF7

Case counts by codes

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 22014 9549 12452
Only index persons 18836 8113 10723
Unadjusted period prevalence (%)
Whole population 0.32 0.27 0.35
Only index persons 0.36 0.30 0.41
Median age at first event (years)
Whole population 9.35 8.90 9.69
Only index persons 9.96 9.47 10.34

-FinnGen-

Key figures

All Female Male
Number of individuals 2832 1485 1347
Unadjusted period prevalence (%) 0.69 0.64 0.74
Median age at first event (years) 9.75 9.70 9.81

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: T1D_EARLY – Type1 diabetes, definitions combined, early onset

GWS hits: 24

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