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Diabetic nephropathy (more control exclusions)

Endpoint Browser PheWeb

DM_NEPHROPATHY_EXMORE

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

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2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — N08.3*
  • Cause of death: ICD-10 — N08.3*

2 out of 7 registries used, show all original rules.

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4. Check minimum number of events

None

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5. Include endpoints

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6. Filter based on genotype QC (FinnGen only)

None

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Control definitions (FinnGen only)

Control exclude DIABETES_FG

Extra metadata

First used in FinnGen datafreeze DF2

Case counts by codes

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FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 42860 16902 25264
Only index persons 29991 11232 18759
Unadjusted period prevalence (%)
Whole population 0.62 0.48 0.71
Only index persons 0.60 0.41 0.72
Median age at first event (years)
Whole population 66.61 69.50 64.74
Only index persons 66.18 68.06 65.06

-FinnGen-

Key figures

All Female Male
Number of individuals 4433 1545 2888
Unadjusted period prevalence (%) 1.27 0.67 1.59
Median age at first event (years) 58.72 51.28 62.70

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: DM_NEPHROPATHY_EXMORE – Diabetic nephropathy (more control exclusions)

GWS hits: 6

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