Type 1 diabetes with renal complications

E4_DM1REN

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

1720

4. Check minimum number of events

None

1720

5. Include endpoints

None

1720

6. Filter based on genotype QC (FinnGen only)

1670

Control definitions (FinnGen only)

Control exclude E4_DIABETES

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF3

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 11272 4330 6764
Only index persons 7967 3102 4865
Unadjusted period prevalence (%)
Whole population 0.16 0.12 0.19
Only index persons 0.16 0.11 0.19
Median age at first event (years)
Whole population 48.39 45.71 49.85
Only index persons 45.65 40.98 48.63

-FinnGen-

Key figures

All Female Male
Number of individuals 1670 731 939
Unadjusted period prevalence (%) 0.43 0.32 0.52
Median age at first event (years) 40.76 34.83 45.37

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: E4_DM1REN – Type 1 diabetes with renal complications

GWS hits: 6

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