No definition available.
Endpoint definition
↥
						Endpoint definition steps | 
					
						FinnGen | 
				
|---|---|
						Phenotype data | 
					429209 | 
								1. Apply sex-specific ruleNone  | 
							429209 | 
								2. Check conditionsNone  | 
							429209 | 
								3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 
 2 out of 7 registries used, show all original rules.  | 
							
								 1720  | 
						
								4. Check minimum number of eventsNone  | 
							1720 | 
								5. Include endpointsNone  | 
							1720 | 
										6. Filter based on genotype QC (FinnGen only) | 
									1670 | 
Control definitions (FinnGen only)
					Control exclude
					E4_DIABETES
				
			Extra metadata
					Level in the ICD hierarchy
					4
				
				
					First used in FinnGen datafreeze
					DF3
				
			Similar endpoints
↥List of similar endpoints to
		
Type 1 diabetes with renal complications
	based on the number of shared cases.
		
		Broader endpoints:
	
- Diabetic nephropathy (more control exclusions)
 - Type 1 diabetes
 - Diabetes mellitus
 - Autoimmune diseases
 - Used for control exclusion in common control thyroid runs
 
		
		Narrower endpoints:
	
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 11272 | 4330 | 6764 | 
| Only index persons | 7967 | 3102 | 4865 | 
| Unadjusted period prevalence (%) | |||
| Whole population | 0.16 | 0.12 | 0.19 | 
| Only index persons | 0.16 | 0.11 | 0.19 | 
| Median age at first event (years) | |||
| Whole population | 48.39 | 45.71 | 49.85 | 
| Only index persons | 45.65 | 40.98 | 48.63 | 
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1670 | 731 | 939 | 
| Unadjusted period prevalence (%) | 0.43 | 0.32 | 0.52 | 
| Median age at first event (years) | 40.76 | 34.83 | 45.37 | 
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: E4_DM1REN – Type 1 diabetes with renal complications
GWS hits: 6
                
                Loading Relationships table