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Psychotic depression

Endpoint Browser PheWeb

F5_DEPRESSION_PSYCHOTIC

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

  • not (F5_SCHIZO
  • or F5_SCHIZOAFF
  • or F5_BIPO
409530

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 — F32.3, F33.3
  • Hospital discharge: ICD-10 — F32.3, F33.3
  • Hospital discharge: ICD-9 — 2961E
  • Cause of death: ICD-10 — F32.3, F33.3
  • Cause of death: ICD-9 — 2961E

3 out of 7 registries used, show all original rules.

2248

4. Check minimum number of events

None

2248

5. Include endpoints

None

2248

6. Filter based on genotype QC (FinnGen only)

2149

Control definitions (FinnGen only)

Control exclude F5_PSYCH, ANTIDEPRESSANTS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF9

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 26662 15718 10707
Only index persons 23000 13838 9162
Unadjusted period prevalence (%)
Whole population 0.39 0.45 0.30
Only index persons 0.45 0.51 0.35
Median age at first event (years)
Whole population 48.70 48.81 48.50
Only index persons 46.51 46.23 46.94

-FinnGen-

Key figures

All Female Male
Number of individuals 2149 1349 800
Unadjusted period prevalence (%) 0.53 0.59 0.44
Median age at first event (years) 47.05 44.43 51.45

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: F5_DEPRESSION_PSYCHOTIC – Psychotic depression

GWS hits: -

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