Cirrhosis, broad definition used in the article https://doi.org/10.1101/594523

CIRRHOSIS_BROAD

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

4503

6. Filter based on genotype QC (FinnGen only)

4379

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF3

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 82343 22329 58113
Only index persons 48746 14732 34014
Unadjusted period prevalence (%)
Whole population 1.37 0.64 1.62
Only index persons 1.07 0.54 1.30
Median age at first event (years)
Whole population 57.17 59.00 56.47
Only index persons 58.89 60.06 58.39

-FinnGen-

Key figures

All Female Male
Number of individuals 4379 1362 3017
Unadjusted period prevalence (%) 1.33 0.59 1.66
Median age at first event (years) 60.07 58.61 60.72

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: CIRRHOSIS_BROAD – Cirrhosis, broad definition used in the article https://doi.org/10.1101/594523

GWS hits: 4

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