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Oesophageal varices

DOID EFO Endpoint Browser PheWeb

I9_VARICVEOES

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — I85
  • Hospital discharge: ICD-9 — 456[0-1]
  • Hospital discharge: ICD-8 — 4560
  • Cause of death: ICD-10 — I85
  • Cause of death: ICD-9 — 456[0-1]
  • Cause of death: ICD-8 — 4560

2 out of 7 registries used, show all original rules.

1140

4. Check minimum number of events

None

1140

5. Include endpoints

None

1140

6. Filter based on genotype QC (FinnGen only)

1102

Control definitions (FinnGen only)

Control exclude I9_DISVEINLYMPH

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I80-I89
Name in latin Varices oesophagi

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 15571 4582 10653
Only index persons 9567 3029 6538
Unadjusted period prevalence (%)
Whole population 0.25 0.13 0.30
Only index persons 0.21 0.11 0.25
Median age at first event (years)
Whole population 59.23 62.25 57.96
Only index persons 60.61 62.62 59.68

-FinnGen-

Key figures

All Female Male
Number of individuals 1102 376 726
Unadjusted period prevalence (%) 0.32 0.16 0.40
Median age at first event (years) 62.15 61.86 62.30

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: I9_VARICVEOES – Oesophageal varices

GWS hits: 3

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