≡ Risteys
FR+FG R10

Documentation Changelog GitHub Contact & Feedback

Alcoholic liver disease

DOID EFO Endpoint Browser PheWeb

K11_ALCOLIV

Hepatitis, Alcoholic: INFLAMMATION of the LIVER due to ALCOHOL ABUSE. It is characterized by NECROSIS of HEPATOCYTES, infiltration by NEUTROPHILS, and deposit of MALLORY BODIES. Depending on its severity, the inflammatory lesion may be reversible or progress to LIVER CIRRHOSIS.

Suggest a new description

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — K70
  • Hospital discharge: ICD-9 — 571[0-3]
  • Hospital discharge: ICD-8 — 5710
  • Cause of death: ICD-10 — K70
  • Cause of death: ICD-9 — 571[0-3]
  • Cause of death: ICD-8 — 5710

2 out of 7 registries used, show all original rules.

3118

4. Check minimum number of events

None

3118

5. Include endpoints

None

3118

6. Filter based on genotype QC (FinnGen only)

3046

Control definitions (FinnGen only)

Control exclude K11_LIVER

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 K70-K77
Name in latin Morbus hepatis alcoholicus

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 68208 15821 50693
Only index persons 38268 9865 28403
Unadjusted period prevalence (%)
Whole population 1.20 0.45 1.42
Only index persons 0.90 0.36 1.08
Median age at first event (years)
Whole population 55.72 56.23 55.54
Only index persons 57.44 57.56 57.40

-FinnGen-

Key figures

All Female Male
Number of individuals 3046 746 2300
Unadjusted period prevalence (%) 1.03 0.32 1.27
Median age at first event (years) 58.35 55.91 59.14

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

↥

Relationships between endpoints

↥

Index endpoint: K11_ALCOLIV – Alcoholic liver disease

GWS hits: 5

loading spinner Loading Relationships table