portal hypertension: Increased blood pressure in the portal venous system. It is most commonly caused by cirrhosis. Other causes include portal vein thrombosis, Budd-Chiari syndrome, and right heart failure. Complications include ascites, esophageal varices, encephalopathy, and splenomegaly.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditionsNone |
429209 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
83 |
4. Check minimum number of eventsNone |
83 |
5. Include endpointsNone |
83 |
6. Filter based on genotype QC (FinnGen only) |
80 |
Control definitions (FinnGen only)
Control exclude
CIRRHOSIS_BROAD
Extra metadata
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
K76
Name in latin
Hypertensio venae portae
Similar endpoints
↥List of similar endpoints to
Hypertension, portal
based on the number of shared cases.
Broader endpoints:
- Cirrhosis, broad definition used in the article https://doi.org/10.1101/594523
- Other diseases of liver
- Diseases of liver
- Gastrointestinal diseases
- Any operation in hilmo
Narrower endpoints:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 745 | 296 | 439 |
| Only index persons | 603 | 241 | 362 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 58.88 | 59.75 | 58.18 |
| Only index persons | 58.65 | 58.48 | 58.77 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 80 | 36 | 44 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | 57.00 | 56.77 | 57.19 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: I9_HYPTENSPOR – Hypertension, portal
GWS hits: -
Loading Relationships table