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Malignant neoplasm, wide definition for exclusion (controls excluding all cancers)

C3_CANCER_WIDE_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C
  • Hospital discharge: ICD-9 1[4-9]|20
  • Hospital discharge: ICD-8 1[4-9]|20
  • Cause of death: ICD-10 C
  • Cause of death: ICD-9 1[4-9]|20
  • Cause of death: ICD-8 1[4-9]|20
  • KELA reimbursements: KELA codes 115|116

3 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude C3_CANCER

Extra metadata

Level in the ICD hierarchy 1
First used in FinnGen datafreeze DF9

Case counts by codes

FinnGen case counts by registry codes:

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Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population - - -
Only index persons - - -
Unadjusted period prevalence (%)
Whole population - - -
Only index persons - - -
Median age at first event (years)
Whole population - - -
Only index persons - - -

-FinnGen-

Key figures

All Female Male
Number of individuals 97960 47368 50592
Unadjusted period prevalence (%) 24.32 20.57 27.83
Median age at first event (years) 64.38 60.71 67.82

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: C3_CANCER_WIDE_EXALLC – Malignant neoplasm, wide definition for exclusion (controls excluding all cancers)

GWS hits: -

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