Malignant neoplasm (controls excluding all cancers)

C3_CANCER_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • KELA reimbursements: KELA codes 115|116|130

1 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy 1
First used in FinnGen datafreeze DF9

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 839528 402694 422373
Only index persons 522509 273218 249291
Unadjusted period prevalence (%)
Whole population 11.73 11.53 11.80
Only index persons 9.79 10.04 9.52
Median age at first event (years)
Whole population 66.26 64.63 67.80
Only index persons 65.86 63.89 68.02

-FinnGen-

Key figures

All Female Male
Number of individuals 87530 42157 45373
Unadjusted period prevalence (%) 21.75 18.31 24.96
Median age at first event (years) 64.41 60.62 67.94

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: C3_CANCER_EXALLC – Malignant neoplasm (controls excluding all cancers)

GWS hits: 54

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