Other malignant neoplasms of skin (=non-melanoma skin cancer) (controls excluding all cancers)

C3_OTHER_SKIN_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

  • not C3_MELANOMA_SKIN
-

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C44
  • Cause of death: ICD-9 173
  • Cause of death: ICD-8 173
  • Cancer registry: Topography ICD-O-3 C44
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude C3_CANCER, C3_CANCER_WIDE
Control conditions not C3_MELANOMA_SKIN

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF9

Similar endpoints

Case counts by codes

FinnGen case counts by registry codes:

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Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 37470 17663 19389
Only index persons 28807 14018 14789
Unadjusted period prevalence (%)
Whole population 0.52 0.51 0.54
Only index persons 0.54 0.52 0.56
Median age at first event (years)
Whole population 77.33 79.11 75.78
Only index persons 77.57 79.14 76.10

-FinnGen-

Key figures

All Female Male
Number of individuals 19077 8828 10249
Unadjusted period prevalence (%) 4.80 3.83 5.64
Median age at first event (years) 67.56 65.88 69.00

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: C3_OTHER_SKIN_EXALLC – Other malignant neoplasms of skin (=non-melanoma skin cancer) (controls excluding all cancers)

GWS hits: 70

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