Antihypertensive medication - note that there are other indications

RX_ANTIHYP

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Medicine purchases: ATC C0[789]

1 out of 7 registries used, show all original rules.

229781

4. Check minimum number of events

Min. number of events 3
229781

5. Include endpoints

None

229781

6. Filter based on genotype QC (FinnGen only)

222557

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2334599 1215225 1102476
Only index persons 2040159 1081643 958516
Unadjusted period prevalence (%)
Whole population 32.79 34.81 30.80
Only index persons 38.27 39.76 36.59
Median age at first event (years)
Whole population 57.85 58.94 56.51
Only index persons 56.16 57.07 55.14

-FinnGen-

Key figures

All Female Male
Number of individuals 222557 113162 109395
Unadjusted period prevalence (%) 54.56 49.14 60.17
Median age at first event (years) 54.48 52.54 56.48

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: RX_ANTIHYP – Antihypertensive medication - note that there are other indications

GWS hits: 230

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