Heart failure and antihypertensive medication

I9_HEARTFAIL_AND_ANTIHYPERT

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

  • RX_ANTIHYP
229781

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

29130

6. Filter based on genotype QC (FinnGen only)

28161

Control definitions (FinnGen only)

Control conditions not RX_ANTIHYP

Extra metadata

First used in FinnGen datafreeze DF5

Case counts by codes

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 392255 208935 178711
Only index persons 291613 157423 134190
Unadjusted period prevalence (%)
Whole population 5.52 5.98 4.99
Only index persons 5.48 5.79 5.12
Median age at first event (years)
Whole population 74.28 76.57 71.66
Only index persons 74.82 77.32 71.88

-FinnGen-

Key figures

All Female Male
Number of individuals 28161 10336 17825
Unadjusted period prevalence (%) 7.85 4.49 9.80
Median age at first event (years) 70.99 71.48 70.70

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: I9_HEARTFAIL_AND_ANTIHYPERT – Heart failure and antihypertensive medication

GWS hits: 42

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