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Alcoholic myopathy

ALCOMYOP

alcoholic cardiomyopathy: Disease of CARDIAC MUSCLE resulting from chronic excessive alcohol consumption. Myocardial damage can be caused by: (1) a toxic effect of alcohol; (2) malnutrition in alcoholics such as THIAMINE DEFICIENCY; or (3) toxic effect of additives in alcoholic beverages such as COBALT. This disease is usually manifested by DYSPNEA and palpitations with CARDIOMEGALY and congestive heart failure (HEART FAILURE).

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G72.1
  • Cause of death: ICD-10 G72.1

2 out of 7 registries used, show all original rules.

31

4. Check minimum number of events

None

31

5. Include endpoints

None

31

6. Filter based on genotype QC (FinnGen only)

30

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G72
Name in latin Myopathia alcoholica

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 528 123 401
Only index persons 419 102 317
Unadjusted period prevalence (%)
Whole population 0.01 0.00 0.01
Only index persons 0.01 0.00 0.01
Median age at first event (years)
Whole population 58.43 59.95 57.98
Only index persons 58.88 60.75 58.28

-FinnGen-

Key figures

All Female Male
Number of individuals 30 7 23
Unadjusted period prevalence (%) 0.01 0.00 0.01
Median age at first event (years) 53.39 53.27 53.43

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: ALCOMYOP – Alcoholic myopathy

GWS hits: -

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