Drug-induced myopathy

G6_DRUGMYOP

muscular disease: Acquired, familial, and congenital disorders of skeletal muscle and smooth muscle.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G72.0#
  • Cause of death: ICD-10 G72.0#

2 out of 7 registries used, show all original rules.

85

4. Check minimum number of events

None

85

5. Include endpoints

None

85

6. Filter based on genotype QC (FinnGen only)

82

Control definitions (FinnGen only)

Control exclude G6_MYONEU

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G72
Name in latin Myopathia medicamento provocata

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1105 444 652
Only index persons 966 397 569
Unadjusted period prevalence (%)
Whole population 0.02 0.01 0.02
Only index persons 0.02 0.01 0.02
Median age at first event (years)
Whole population 64.92 70.20 61.21
Only index persons 64.72 69.67 61.26

-FinnGen-

Key figures

All Female Male
Number of individuals 82 33 49
Unadjusted period prevalence (%) 0.02 0.01 0.03
Median age at first event (years) 64.49 58.67 68.41

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: G6_DRUGMYOP – Drug-induced myopathy

GWS hits: -

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