type II diabetes mellitus: A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditions
|
417843 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
67620 |
6. Filter based on genotype QC (FinnGen only) |
65083 |
Control definitions (FinnGen only)
Control exclude
DIABETES_FG
Control conditions
not E4_DM1
Extra metadata
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Type 2 diabetes, definitions combined
based on the number of shared cases.
Broader endpoints:
- Type 2 diabetes, definitions combined, including avohilmo
- Type 2 diabetes
- Diabetes, varying definitions
- Diabetes mellitus
- Endocrine, nutritional and metabolic diseases
Narrower endpoints:
Case counts by codes
↥FinnGen case counts by registry codes:
No data for upset plot.
No data for upset table.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 672907 | 323104 | 343619 |
| Only index persons | 555680 | 265660 | 290020 |
| Unadjusted period prevalence (%) | |||
| Whole population | 9.41 | 9.25 | 9.60 |
| Only index persons | 10.45 | 9.77 | 11.07 |
| Median age at first event (years) | |||
| Whole population | 63.87 | 66.12 | 61.70 |
| Only index persons | 62.04 | 63.76 | 60.46 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 65083 | 28926 | 36157 |
| Unadjusted period prevalence (%) | 16.63 | 12.56 | 19.89 |
| Median age at first event (years) | 60.57 | 59.68 | 61.28 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: T2D – Type 2 diabetes, definitions combined
GWS hits: 245
Loading Relationships table