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Type 2 diabetes


type II diabetes mellitus: A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity.

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Endpoint definition

Endpoint definition steps


Phenotype data


1. Apply sex-specific rule



2. Check conditions



3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E11
  • Cause of death: ICD-10 E11
  • Medicine purchases: ATC A10B

3 out of 7 registries used, show all original rules.


4. Check minimum number of events

Min. number of events 3

5. Include endpoints


6. Filter based on genotype QC (FinnGen only)


Control definitions (FinnGen only)

Control exclude E4_DIABETES

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF9
Parent code in ICD-10 E10-E14

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics


This endpoint is excluded from FinRegistry analyses (omitted endpoint).


Key figures

All Female Male
Number of individuals 71816 31907 39909
Unadjusted period prevalence (%) 18.35 13.86 21.95
Median age at first event (years) 59.59 58.64 60.35


Age distribution of first events


Year distribution of first events


Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: E4_DM2 – Type 2 diabetes

GWS hits: -

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