psoriasis: An autoimmune condition characterized by red, well-delineated plaques with silvery scales that are usually on the extensor surfaces and scalp. They can occasionally present with these manifestations: pustules; erythema and scaling in intertriginous areas, and erythroderma, that are often distributed on extensor surfaces and scalp.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditions
|
6672 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
937 |
4. Check minimum number of eventsNone |
937 |
5. Include endpointsNone |
937 |
6. Filter based on genotype QC (FinnGen only) |
901 |
Control definitions (FinnGen only)
Control exclude
L12_PAPULOSQUAMOUS
Control conditions
not L12_PSORI_VULG
Extra metadata
First used in FinnGen datafreeze
DF3
Similar endpoints
↥List of similar endpoints to
Psoriasis (vulgaris), strict definition
based on the number of shared cases.
Broader endpoints:
- Psoriasis vulgaris
- Psoriasis
- Papulosquamous disorders
- Autoimmune diseases related-to ILD
- Autoimmune diseases
Narrower endpoints:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4808 | 1617 | 3168 |
| Only index persons | 4482 | 1538 | 2944 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.07 | 0.05 | 0.09 |
| Only index persons | 0.09 | 0.06 | 0.11 |
| Median age at first event (years) | |||
| Whole population | 51.67 | 54.18 | 50.42 |
| Only index persons | 51.17 | 53.78 | 49.80 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 901 | 348 | 553 |
| Unadjusted period prevalence (%) | 0.25 | 0.15 | 0.30 |
| Median age at first event (years) | 51.50 | 53.06 | 50.52 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: PSORI_STRICT – Psoriasis (vulgaris), strict definition
GWS hits: 6
Loading Relationships table