Primary gonarthrosis, bilateral

PRIM_KNEEARTHROSIS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M17.0
  • Cause of death: ICD-10 M17.0

2 out of 7 registries used, show all original rules.

19101

4. Check minimum number of events

None

19101

5. Include endpoints

None

19101

6. Filter based on genotype QC (FinnGen only)

18562

Control definitions (FinnGen only)

Control exclude KNEE_ARTHROSIS

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 M17
Name in latin Gonarthrosis primaria bilateralis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 159545 103312 55740
Only index persons 149586 97271 52315
Unadjusted period prevalence (%)
Whole population 2.46 2.96 1.56
Only index persons 3.02 3.58 2.00
Median age at first event (years)
Whole population 68.02 69.24 65.73
Only index persons 67.41 68.62 65.14

-FinnGen-

Key figures

All Female Male
Number of individuals 18562 11381 7181
Unadjusted period prevalence (%) 4.56 4.94 3.95
Median age at first event (years) 64.22 63.65 65.12

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: PRIM_KNEEARTHROSIS – Primary gonarthrosis, bilateral

GWS hits: 36

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