Secondary parkinsonism (more control exclusions)

PD2ND_EXMORE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G21
  • Hospital discharge: ICD-9 3321
  • Cause of death: ICD-10 G21
  • Cause of death: ICD-9 3321

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude G6_PARKINSON, F5_PSYCH, NEURODIS

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 G20-G26
Name in latin Parkinsonismus secundarius

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 11158 5439 5530
Only index persons 7519 3804 3715
Unadjusted period prevalence (%)
Whole population 0.16 0.16 0.15
Only index persons 0.14 0.14 0.14
Median age at first event (years)
Whole population 71.35 72.01 70.61
Only index persons 69.43 70.60 68.23

-FinnGen-

Key figures

All Female Male
Number of individuals 784 323 461
Unadjusted period prevalence (%) 0.21 0.14 0.25
Median age at first event (years) 65.58 65.13 65.90

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: PD2ND_EXMORE – Secondary parkinsonism (more control exclusions)

GWS hits: 1

loading spinner Loading Relationships table