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Polymyalgia rheumatica

DOID EFO Endpoint Browser PheWeb

M13_POLYMYALGIA

polymyalgia rheumatica: Polymyalgia rheumatica is a common inflammatory condition that often affects people over the age of 50 years. Characteristic symptoms are shoulder and hip girdle pain and prolonged morning stiffness. Markers of inflammation are often elevated.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — M35.3
  • Hospital discharge: ICD-9 — 725
  • Hospital discharge: ICD-8 — 4463
  • Cause of death: ICD-10 — M35.3
  • Cause of death: ICD-9 — 725
  • Cause of death: ICD-8 — 4463

2 out of 7 registries used, show all original rules.

3986

4. Check minimum number of events

None

3986

5. Include endpoints

None

3986

6. Filter based on genotype QC (FinnGen only)

3871

Control definitions (FinnGen only)

Control exclude M13_SYSTCONNECT

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M35
Name in latin Polymyalgia rheumatica

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 42642 28465 13837
Only index persons 34295 22973 11322
Unadjusted period prevalence (%)
Whole population 0.67 0.82 0.39
Only index persons 0.71 0.84 0.43
Median age at first event (years)
Whole population 74.56 75.24 73.15
Only index persons 73.96 74.64 72.56

-FinnGen-

Key figures

All Female Male
Number of individuals 3871 2227 1644
Unadjusted period prevalence (%) 0.94 0.97 0.90
Median age at first event (years) 70.64 69.94 71.59

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: M13_POLYMYALGIA – Polymyalgia rheumatica

GWS hits: 1

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