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Myositis

DOID EFO Endpoint Browser PheWeb

M13_MYOSITIS

myositis: An inflammatory disease involving a pathogenic inflammatory response in the muscle tissue.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — M60
  • Hospital discharge: ICD-9 — 7280
  • Hospital discharge: ICD-8 — 732
  • Cause of death: ICD-10 — M60
  • Cause of death: ICD-9 — 7280
  • Cause of death: ICD-8 — 732

2 out of 7 registries used, show all original rules.

790

4. Check minimum number of events

None

790

5. Include endpoints

None

790

6. Filter based on genotype QC (FinnGen only)

759

Control definitions (FinnGen only)

Control exclude M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M60-M63
Name in latin Myositis

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 7204 3423 3738
Only index persons 6302 3063 3239
Unadjusted period prevalence (%)
Whole population 0.10 0.10 0.10
Only index persons 0.12 0.11 0.12
Median age at first event (years)
Whole population 49.20 52.96 45.69
Only index persons 48.87 52.23 45.69

-FinnGen-

Key figures

All Female Male
Number of individuals 759 394 365
Unadjusted period prevalence (%) 0.19 0.17 0.20
Median age at first event (years) 55.73 52.63 59.07

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: M13_MYOSITIS – Myositis

GWS hits: 1

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