Soft tissue disorders

M13_SOFTTISSUE

musculoskeletal system disease: A disease involving the musculoskeletal system. [database_cross_reference: MONDO:DesignPattern]

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M60-M79
  • Cause of death: ICD-10 M60-M79

2 out of 7 registries used, show all original rules.

110307

4. Check minimum number of events

None

110307

5. Include endpoints

116585

6. Filter based on genotype QC (FinnGen only)

112572

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1074859 583578 485541
Only index persons 997467 552201 445266
Unadjusted period prevalence (%)
Whole population 15.24 16.72 13.57
Only index persons 18.83 20.30 17.00
Median age at first event (years)
Whole population 50.48 50.99 49.89
Only index persons 50.17 50.72 49.50

-FinnGen-

Key figures

All Female Male
Number of individuals 112572 66556 46016
Unadjusted period prevalence (%) 27.43 28.90 25.31
Median age at first event (years) 52.05 50.29 54.60

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: M13_SOFTTISSUE – Soft tissue disorders

GWS hits: 15

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