musculoskeletal system disease: A disease involving the musculoskeletal system. [database_cross_reference: MONDO:DesignPattern]
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditionsNone |
429209 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
110307 |
4. Check minimum number of eventsNone |
110307 |
5. Include endpoints |
116585 |
6. Filter based on genotype QC (FinnGen only) |
112572 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Soft tissue disorders
based on the number of shared cases.
Broader endpoints:
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
Narrower endpoints:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1074859 | 583578 | 485541 |
| Only index persons | 997467 | 552201 | 445266 |
| Unadjusted period prevalence (%) | |||
| Whole population | 15.24 | 16.72 | 13.57 |
| Only index persons | 18.83 | 20.30 | 17.00 |
| Median age at first event (years) | |||
| Whole population | 50.48 | 50.99 | 49.89 |
| Only index persons | 50.17 | 50.72 | 49.50 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 112572 | 66556 | 46016 |
| Unadjusted period prevalence (%) | 27.43 | 28.90 | 25.31 |
| Median age at first event (years) | 52.05 | 50.29 | 54.60 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: M13_SOFTTISSUE – Soft tissue disorders
GWS hits: 15
Loading Relationships table