dermatomyositis: Dermatomyositis (DM) is a type of idiopathic inflammatory myopathy characterized by evocative skin lesions and symmetrical proximal muscle weakness.
Endpoint definition
↥| Endpoint definition steps | FinnGen | 
|---|---|
| Phenotype data | 429209 | 
| 1. Apply sex-specific ruleNone | 429209 | 
| 2. Check conditionsNone | 429209 | 
| 3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. | 157 | 
| 4. Check minimum number of eventsNone | 157 | 
| 5. Include endpointsNone | 157 | 
| 6. Filter based on genotype QC (FinnGen only) | 153 | 
Control definitions (FinnGen only)
					Control exclude
					M13_SYSTCONNECT
				
			Extra metadata
					Level in the ICD hierarchy
					4
				
				
					First used in FinnGen datafreeze
					DF2
				
				
					Parent code in ICD-10
					M33
				
				
					Name in latin
					Dermato[poly]myositis non specificata
				
			Similar endpoints
↥List of similar endpoints to
		
Dermatopolymyositis, unspecified
	based on the number of shared cases.
		
		Broader endpoints:
	
- Dermatopolymyositis (FG)
- Dermatopolymyositis
- Systemic connective tissue disorders
- Autoimmune diseases related-to ILD
- Finngen Rheumatological endpoints
		
		Narrower endpoints:
	
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 919 | 568 | 346 | 
| Only index persons | 811 | 503 | 308 | 
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.02 | 0.01 | 
| Only index persons | 0.02 | 0.02 | 0.01 | 
| Median age at first event (years) | |||
| Whole population | 59.15 | 58.28 | 60.73 | 
| Only index persons | 57.73 | 56.78 | 59.29 | 
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 153 | 88 | 65 | 
| Unadjusted period prevalence (%) | 0.04 | 0.04 | 0.04 | 
| Median age at first event (years) | 56.56 | 53.30 | 60.97 | 
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: M13_DERMATOPOLYNAS – Dermatopolymyositis, unspecified
GWS hits: -
                
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