Gonarthrosis, primary, with knee surgery

M13_ARTHROSIS_KNEE_PRIM_KNEESURG

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

  • M13_ARTHROSIS_KNEE_PRIM_ICD10
44989

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Operations: NOMESCO codes ^NGB|^NGC

1 out of 7 registries used, show all original rules.

21583

4. Check minimum number of events

None

21583

5. Include endpoints

None

21583

6. Filter based on genotype QC (FinnGen only)

21059

Control definitions (FinnGen only)

Control conditions not M13_ARTHROSIS_KNEE_PRIM_ICD10

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF3

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 167712 109905 57409
Only index persons 159788 105159 54629
Unadjusted period prevalence (%)
Whole population 2.61 3.15 1.60
Only index persons 3.26 3.87 2.09
Median age at first event (years)
Whole population 69.62 70.34 68.20
Only index persons 69.30 70.03 67.88

-FinnGen-

Key figures

All Female Male
Number of individuals 21059 12950 8109
Unadjusted period prevalence (%) 5.18 5.62 4.46
Median age at first event (years) 67.04 66.70 67.57

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: M13_ARTHROSIS_KNEE_PRIM_KNEESURG – Gonarthrosis, primary, with knee surgery

GWS hits: 44

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