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Mental retardation (more control exclusions)

Endpoint Browser PheWeb

KRA_PSY_MENTALRET_EXMORE

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

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2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — F70-F79
  • Hospital discharge: ICD-9 — 31[7-9]
  • Hospital discharge: ICD-8 — 31[1-5]
  • Cause of death: ICD-10 — F70-F79
  • Cause of death: ICD-9 — 31[7-9]
  • Cause of death: ICD-8 — 31[1-5]

2 out of 7 registries used, show all original rules.

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4. Check minimum number of events

None

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5. Include endpoints

None

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6. Filter based on genotype QC (FinnGen only)

None

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Control definitions (FinnGen only)

Control exclude KRA_PSY_ANYMENTAL

Extra metadata

First used in FinnGen datafreeze DF2

Case counts by codes

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FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 42454 18381 23958
Only index persons 34472 15015 19457
Unadjusted period prevalence (%)
Whole population 0.61 0.53 0.67
Only index persons 0.66 0.55 0.74
Median age at first event (years)
Whole population 15.58 17.76 13.76
Only index persons 15.95 17.81 14.51

-FinnGen-

Key figures

All Female Male
Number of individuals 1254 617 637
Unadjusted period prevalence (%) 0.31 0.27 0.35
Median age at first event (years) 23.46 24.48 22.48

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: KRA_PSY_MENTALRET_EXMORE – Mental retardation (more control exclusions)

GWS hits: 2

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