Crohn's disease (strict) with PSC

K11_CD_STRICT_PSC

ileocolitis: Ileocolitis or ileal Crohn's is the most common type of Crohn's disease. It affects both the ileum (small intestine) and the colon.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

  • K11_CHOLANGI_STRICT
  • and K11_CD_STRICT
53

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

53

6. Filter based on genotype QC (FinnGen only)

51

Control definitions (FinnGen only)

Control exclude K11_IBD, K11_CHOLANGI
Control conditions not K11_CHOLANGI_STRICT
and not K11_CD_STRICT

Extra metadata

First used in FinnGen datafreeze DF3

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 159 66 91
Only index persons 154 65 89
Unadjusted period prevalence (%)
Whole population 0.00 0.00 0.00
Only index persons 0.00 0.00 0.00
Median age at first event (years)
Whole population 30.30 29.94 30.31
Only index persons 30.01 29.61 30.31

-FinnGen-

Key figures

All Female Male
Number of individuals 51 26 25
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 31.55 30.94 32.18

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: K11_CD_STRICT_PSC – Crohn's disease (strict) with PSC

GWS hits: -

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