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Rheumatic heart disease, other

DOID EFO Endpoint Browser PheWeb

I9_RHEUOTHHRT

rheumatic heart disease: Cardiac manifestation of systemic rheumatological conditions, such as RHEUMATIC FEVER. Rheumatic heart disease can involve any part the heart, most often the HEART VALVES and the ENDOCARDIUM.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — I09
  • Hospital discharge: ICD-9 — 3920A|393|39[7-8]
  • Hospital discharge: ICD-8 — 3920|393|3979|398
  • Cause of death: ICD-10 — I09
  • Cause of death: ICD-9 — 3920A|393|39[7-8]
  • Cause of death: ICD-8 — 3920|393|3979|398

2 out of 7 registries used, show all original rules.

55

4. Check minimum number of events

None

55

5. Include endpoints

None

55

6. Filter based on genotype QC (FinnGen only)

54

Control definitions (FinnGen only)

Control exclude I9_RHEUFEV

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I05-I09
Name in latin Alii morbi cordis rheumatici

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1169 566 564
Only index persons 564 283 281
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.02
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 54.10 56.37 51.36
Only index persons 39.07 41.36 36.76

-FinnGen-

Key figures

All Female Male
Number of individuals 54 33 21
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 32.68 32.69 32.67

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: I9_RHEUOTHHRT – Rheumatic heart disease, other

GWS hits: -

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