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Status post-ami

DOID EFO Endpoint Browser PheWeb

I9_POSTAMI

heart aneurysm: A localized bulging or dilatation in the muscle wall of a heart (myocardium), usually in the left ventricle. Blood-filled aneurysms are dangerous because they may burst. Fibrous aneurysms interfere with the heart function through the loss of contractility. True aneurysm is bound by the vessel wall or cardiac wall. False aneurysms are hematoma caused by myocardial rupture.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — I25.3
  • Hospital discharge: ICD-9 — 412
  • Hospital discharge: ICD-8 — 412
  • Cause of death: ICD-10 — I25.3
  • Cause of death: ICD-9 — 412
  • Cause of death: ICD-8 — 412

2 out of 7 registries used, show all original rules.

3324

4. Check minimum number of events

None

3324

5. Include endpoints

None

3324

6. Filter based on genotype QC (FinnGen only)

3221

Control definitions (FinnGen only)

Control exclude I9_ISCHHEART

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I25
Name in latin Aneurysma cordis

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 108486 33890 70276
Only index persons 20386 6515 13871
Unadjusted period prevalence (%)
Whole population 1.75 0.97 1.96
Only index persons 0.44 0.24 0.53
Median age at first event (years)
Whole population 63.64 67.62 61.78
Only index persons 54.84 56.89 53.89

-FinnGen-

Key figures

All Female Male
Number of individuals 3221 480 2741
Unadjusted period prevalence (%) 1.31 0.21 1.51
Median age at first event (years) 56.67 56.64 56.67

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: I9_POSTAMI – Status post-ami

GWS hits: 7

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