atrial fibrillation: A disorder characterized by an electrocardiographic finding of a supraventricular arrhythmia characterized by the replacement of consistent P waves by rapid oscillations or fibrillatory waves that vary in size, shape and timing and are accompanied by an irregular ventricular response. (CDISC)
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditions
|
52261 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
31678 |
4. Check minimum number of eventsNone |
31678 |
5. Include endpointsNone |
31678 |
6. Filter based on genotype QC (FinnGen only) |
30785 |
Control definitions (FinnGen only)
Control exclude
FG_CVD
Control conditions
not I9_AF
Extra metadata
First used in FinnGen datafreeze
DF3
Similar endpoints
↥List of similar endpoints to
Atrial fibrillation and flutter with reimbursement
based on the number of shared cases.
Broader endpoints:
- Atrial fibrillation and flutter
- Cardiac arrhythmias
- Other heart diseases
- Other heart diseases
- Cardiovascular diseases (excluding rheumatic etc)
Narrower endpoints:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 271797 | 130007 | 140171 |
| Only index persons | 240475 | 116642 | 123833 |
| Unadjusted period prevalence (%) | |||
| Whole population | 3.81 | 3.72 | 3.92 |
| Only index persons | 4.51 | 4.29 | 4.73 |
| Median age at first event (years) | |||
| Whole population | 73.73 | 76.89 | 70.86 |
| Only index persons | 74.23 | 77.39 | 71.25 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 30785 | 12649 | 18136 |
| Unadjusted period prevalence (%) | 8.13 | 5.49 | 9.98 |
| Median age at first event (years) | 72.05 | 73.58 | 70.99 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: I9_AF_REIMB – Atrial fibrillation and flutter with reimbursement
GWS hits: 95
Loading Relationships table