Diseases of middle ear and mastoid

H8_MIDDLEMASTOID

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H65-H75
  • Cause of death: ICD-10 H65-H75

2 out of 7 registries used, show all original rules.

18163

4. Check minimum number of events

None

18163

5. Include endpoints

28717

6. Filter based on genotype QC (FinnGen only)

27527

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 653223 287415 364512
Only index persons 498465 221011 277454
Unadjusted period prevalence (%)
Whole population 9.31 8.23 10.18
Only index persons 9.50 8.12 10.59
Median age at first event (years)
Whole population 2.63 2.93 2.26
Only index persons 3.07 3.66 2.60

-FinnGen-

Key figures

All Female Male
Number of individuals 27527 15894 11633
Unadjusted period prevalence (%) 6.69 6.90 6.40
Median age at first event (years) 9.54 7.11 12.85

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: H8_MIDDLEMASTOID – Diseases of middle ear and mastoid

GWS hits: 14

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