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Perforation of tympanic membrane

DOID EFO Endpoint Browser PheWeb

H8_PERFORATION

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H72
  • Hospital discharge: ICD-9 — 3842
  • Cause of death: ICD-10 — H72
  • Cause of death: ICD-9 — 3842

2 out of 7 registries used, show all original rules.

3240

4. Check minimum number of events

None

3240

5. Include endpoints

None

3240

6. Filter based on genotype QC (FinnGen only)

3085

Control definitions (FinnGen only)

Control exclude H8_MIDDLEMASTOID

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H65-H75
Name in latin Perforatio membranae tympanicae

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 39492 18838 20408
Only index persons 35816 17317 18499
Unadjusted period prevalence (%)
Whole population 0.55 0.54 0.57
Only index persons 0.67 0.64 0.71
Median age at first event (years)
Whole population 38.96 43.48 34.79
Only index persons 39.96 44.51 35.70

-FinnGen-

Key figures

All Female Male
Number of individuals 3085 1695 1390
Unadjusted period prevalence (%) 0.75 0.74 0.76
Median age at first event (years) 51.94 49.27 55.20

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: H8_PERFORATION – Perforation of tympanic membrane

GWS hits: 3

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