Inflammatory diseases of the central nervous system

G6_NEUINFL

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G00-G09
  • Cause of death: ICD-10 G00-G09

2 out of 7 registries used, show all original rules.

1867

4. Check minimum number of events

None

1867

5. Include endpoints

2755

6. Filter based on genotype QC (FinnGen only)

2656

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 30865 14355 16249
Only index persons 25199 12176 13023
Unadjusted period prevalence (%)
Whole population 0.43 0.41 0.45
Only index persons 0.47 0.45 0.50
Median age at first event (years)
Whole population 36.98 38.34 35.46
Only index persons 33.30 35.46 31.28

-FinnGen-

Key figures

All Female Male
Number of individuals 2656 1424 1232
Unadjusted period prevalence (%) 0.65 0.62 0.68
Median age at first event (years) 40.68 36.38 45.66

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: G6_NEUINFL – Inflammatory diseases of the central nervous system

GWS hits: -

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