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Bacterial meningitis

DOID EFO Endpoint Browser PheWeb

G6_MENINGBACT

bacterial meningitis: Inflammation of the membranes surrounding the brain and spinal cord due to a bacterial infection.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — G0[0-1]
  • Hospital discharge: ICD-9 — 320
  • Hospital discharge: ICD-8 — 320
  • Cause of death: ICD-10 — G0[0-1]
  • Cause of death: ICD-9 — 320
  • Cause of death: ICD-8 — 320

2 out of 7 registries used, show all original rules.

1087

4. Check minimum number of events

None

1087

5. Include endpoints

None

1087

6. Filter based on genotype QC (FinnGen only)

1055

Control definitions (FinnGen only)

Control exclude G6_NEUINFL

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 13164 5855 7210
Only index persons 10528 4917 5611
Unadjusted period prevalence (%)
Whole population 0.19 0.17 0.20
Only index persons 0.20 0.18 0.21
Median age at first event (years)
Whole population 26.64 28.04 25.10
Only index persons 22.93 25.96 20.28

-FinnGen-

Key figures

All Female Male
Number of individuals 1055 547 508
Unadjusted period prevalence (%) 0.26 0.24 0.28
Median age at first event (years) 27.89 26.83 29.04

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: G6_MENINGBACT – Bacterial meningitis

GWS hits: -

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