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Acute disseminated encephalitis/encephalomyelitis

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G6_ADEM

acute disseminated encephalomyelitis: An encephalomyelitis characterized by inflammation located_in brain and located_in spinal cord that damages myelin. It usually occurs after viral infection, but also following vaccination, bacterial or parasitic infection.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — G04.0#
  • Hospital discharge: ICD-9 — 3235A
  • Hospital discharge: ICD-8 — 32300
  • Cause of death: ICD-10 — G04.0#
  • Cause of death: ICD-9 — 3235A
  • Cause of death: ICD-8 — 32300

2 out of 7 registries used, show all original rules.

57

4. Check minimum number of events

None

57

5. Include endpoints

None

57

6. Filter based on genotype QC (FinnGen only)

55

Control definitions (FinnGen only)

Control exclude G6_NEUINFL

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G04
Name in latin Encephalitis disseminata acuta

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 676 304 364
Only index persons 537 257 280
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 21.71 24.51 18.75
Only index persons 20.47 23.38 17.79

-FinnGen-

Key figures

All Female Male
Number of individuals 55 32 23
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 26.36 24.02 29.61

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: G6_ADEM – Acute disseminated encephalitis/encephalomyelitis

GWS hits: -

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