post-traumatic stress disorder: An anxiety disorder precipitated by an experience of intense fear or horror while exposed to a traumatic (especially life-threatening) event. The disorder is characterized by intrusive recurring thoughts or images of the traumatic event; avoidance of anything associated with the event; a state of hyperarousal and diminished emotional responsiveness. These symptoms are present for at least one month and the disorder is usually long-term.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditionsNone |
429209 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
2839 |
4. Check minimum number of eventsNone |
2839 |
5. Include endpointsNone |
2839 |
6. Filter based on genotype QC (FinnGen only) |
2615 |
Control definitions (FinnGen only)
Control exclude
F5_NEUROTIC
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
F43
Name in latin
Perturbatio stressualis posttraumatica
Similar endpoints
↥List of similar endpoints to
Post-traumatic stress disorder
based on the number of shared cases.
Broader endpoints:
- Neurotic, stress-related and somatoform disorders
- Anxiety disorders
- Anxiety disorders (more control exclusions)
- Any mental disorder
- Psychiatric diseases
Narrower endpoints:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 30821 | 21836 | 8585 |
| Only index persons | 29539 | 21436 | 8103 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.52 | 0.63 | 0.24 |
| Only index persons | 0.66 | 0.79 | 0.31 |
| Median age at first event (years) | |||
| Whole population | 28.54 | 27.97 | 29.72 |
| Only index persons | 28.40 | 27.93 | 29.67 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2615 | 2152 | 463 |
| Unadjusted period prevalence (%) | 0.81 | 0.93 | 0.25 |
| Median age at first event (years) | 34.73 | 33.23 | 41.68 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: F5_PTSD – Post-traumatic stress disorder
GWS hits: -
Loading Relationships table