Recurrent or chronic depression

F5_DEPRESSION_RECURRENT

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

  • not (F5_SCHIZO
  • or F5_SCHIZOAFF
  • or F5_BIPO
409530

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 F33
  • Hospital discharge: ICD-10 F33
  • Cause of death: ICD-10 F33

3 out of 7 registries used, show all original rules.

20140

4. Check minimum number of events

None

20140

5. Include endpoints

None

20140

6. Filter based on genotype QC (FinnGen only)

19387

Control definitions (FinnGen only)

Control exclude F5_PSYCH, ANTIDEPRESSANTS

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF10

Similar endpoints

List of similar endpoints to Recurrent or chronic depression based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

None

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 178931 119504 58529
Only index persons 173320 116960 56360
Unadjusted period prevalence (%)
Whole population 2.83 3.42 1.64
Only index persons 3.60 4.30 2.15
Median age at first event (years)
Whole population 40.62 40.01 41.91
Only index persons 40.23 39.65 41.43

-FinnGen-

Key figures

All Female Male
Number of individuals 19387 14455 4932
Unadjusted period prevalence (%) 5.37 6.28 2.71
Median age at first event (years) 44.26 42.86 48.36

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: F5_DEPRESSION_RECURRENT – Recurrent or chronic depression

GWS hits: 15

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