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Crohn's disease of large intestine

DOID EFO Endpoint Browser PheWeb

CHRONLARGE

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — K50.1
  • Cause of death: ICD-10 — K50.1

2 out of 7 registries used, show all original rules.

1789

4. Check minimum number of events

None

1789

5. Include endpoints

None

1789

6. Filter based on genotype QC (FinnGen only)

1731

Control definitions (FinnGen only)

Control exclude K11_ENERCOLNONINF

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K50
Name in latin Colitis regionalis

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 11142 5575 5526
Only index persons 10570 5321 5249
Unadjusted period prevalence (%)
Whole population 0.16 0.16 0.15
Only index persons 0.20 0.20 0.20
Median age at first event (years)
Whole population 40.90 41.88 39.80
Only index persons 40.05 41.07 39.01

-FinnGen-

Key figures

All Female Male
Number of individuals 1731 975 756
Unadjusted period prevalence (%) 0.42 0.42 0.42
Median age at first event (years) 42.50 41.10 44.30

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: CHRONLARGE – Crohn's disease of large intestine

GWS hits: 7

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