Multiple myeloma and malignant plasma cell neoplasms (controls excluding all cancers)

CD2_MULTIPLE_MYELOMA_PLASMA_CELL_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C90
  • Hospital discharge: ICD-9 203
  • Hospital discharge: ICD-8 203
  • Cause of death: ICD-10 C90
  • Cause of death: ICD-9 203
  • Cause of death: ICD-8 203

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude C3_CANCER

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF8
Parent code in ICD-10 C81-C96
Name in latin Myeloma multiplex et neoplasmata maligna plasmacytorum

Similar endpoints

List of similar endpoints to Multiple myeloma and malignant plasma cell neoplasms (controls excluding all cancers) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Case counts by codes

FinnGen case counts by registry codes:

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Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 16914 8107 8521
Only index persons 10057 4883 5174
Unadjusted period prevalence (%)
Whole population 0.24 0.23 0.24
Only index persons 0.19 0.18 0.20
Median age at first event (years)
Whole population 70.22 71.10 69.40
Only index persons 70.38 71.29 69.52

-FinnGen-

Key figures

All Female Male
Number of individuals 1337 583 754
Unadjusted period prevalence (%) 0.34 0.25 0.41
Median age at first event (years) 68.79 67.66 69.67

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: CD2_MULTIPLE_MYELOMA_PLASMA_CELL_EXALLC – Multiple myeloma and malignant plasma cell neoplasms (controls excluding all cancers)

GWS hits: 1

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