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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart C3_GBM_EXALLC for full statistics.

Brain glioblastoma


brain glioblastoma: A WHO grade IV malignant astrocytic tumor that arises from the brain, usually the cerebral hemispheres. It is characterized by the presence of poorly differentiated astrocytes, cellular polymorphism, nuclear atypia, and increased mitotic activity. The prognosis is poor.

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Endpoint definition

Endpoint definition steps


Phenotype data


1. Apply sex-specific rule



2. Check conditions

  • HLP_C3_GBM

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C71
  • Cause of death: ICD-9 191
  • Cause of death: ICD-8 191
  • Cancer registry: Topography ICD-O-3 C71
  • Cancer registry: Morphology ICD-O-3 9440
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.


4. Check minimum number of events



5. Include endpoints


6. Filter based on genotype QC (FinnGen only)


Control definitions (FinnGen only)

Control conditions not HLP_C3_GBM

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF8

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics


This endpoint is excluded from FinRegistry analyses (omitted endpoint).


Key figures

All Female Male
Number of individuals 253 95 158
Unadjusted period prevalence (%) 0.07 0.04 0.09
Median age at first event (years) 66.08 66.18 66.03


Age distribution of first events


Year distribution of first events


Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_GBM – Brain glioblastoma

GWS hits: -

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