Malignant neoplasm of bladder (controls excluding all cancers)

C3_BLADDER_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C67
  • Cause of death: ICD-9 188
  • Cause of death: ICD-8 188
  • Cancer registry: Topography ICD-O-3 C67
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF9

Case counts by codes

FinnGen case counts by registry codes:

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Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 26494 5491 20344
Only index persons 15280 3598 11682
Unadjusted period prevalence (%)
Whole population 0.49 0.16 0.57
Only index persons 0.37 0.13 0.45
Median age at first event (years)
Whole population 71.39 73.24 70.91
Only index persons 71.24 72.69 70.79

-FinnGen-

Key figures

All Female Male
Number of individuals 2193 338 1855
Unadjusted period prevalence (%) 0.89 0.15 1.02
Median age at first event (years) 70.40 67.36 70.95

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: C3_BLADDER_EXALLC – Malignant neoplasm of bladder (controls excluding all cancers)

GWS hits: 3

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