Autoimmune diseases excluding thyroid diseases, strict definition

AUTOIMMUNE_NONTHYROID_STRICT

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

  • not (HYPOTHY_LEVOTHY
  • or GRAVES_COND
  • or E4_HYTHY_AI_STRICT
  • or AUTOIMMUNE_HYPERTHYROIDISM
372379

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

58619

6. Filter based on genotype QC (FinnGen only)

56628

Control definitions (FinnGen only)

Control conditions not (HYPOTHY_LEVOTHY
or GRAVES_COND
or E4_HYTHY_AI_STRICT
or AUTOIMMUNE_HYPERTHYROIDISM

Extra metadata

First used in FinnGen datafreeze DF7

Case counts by codes

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 564564 288660 270362
Only index persons 455695 236746 218949
Unadjusted period prevalence (%)
Whole population 7.90 8.27 7.55
Only index persons 8.54 8.70 8.36
Median age at first event (years)
Whole population 49.13 50.07 47.92
Only index persons 45.52 46.35 44.62

-FinnGen-

Key figures

All Female Male
Number of individuals 56628 29869 26759
Unadjusted period prevalence (%) 13.80 12.97 14.72
Median age at first event (years) 46.81 44.13 49.81

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: AUTOIMMUNE_NONTHYROID_STRICT – Autoimmune diseases excluding thyroid diseases, strict definition

GWS hits: 57

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