Autoimmune diseases excluding thyroid diseases

AUTOIMMUNE_NONTHYROID

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

  • not (E4_HYTHY_AI_STRICT
  • or AUTOIMMUNE_HYPERTHYROIDISM
  • or E4_GRAVES_STRICT
379002

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

60184

6. Filter based on genotype QC (FinnGen only)

58156

Control definitions (FinnGen only)

Control conditions not (E4_HYTHY_AI_STRICT
or AUTOIMMUNE_HYPERTHYROIDISM
or E4_GRAVES_STRICT

Extra metadata

First used in FinnGen datafreeze DF7

Case counts by codes

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 574184 296204 272401
Only index persons 464635 243793 220842
Unadjusted period prevalence (%)
Whole population 8.04 8.48 7.61
Only index persons 8.71 8.96 8.43
Median age at first event (years)
Whole population 49.23 50.20 47.97
Only index persons 45.70 46.60 44.70

-FinnGen-

Key figures

All Female Male
Number of individuals 58156 31048 27108
Unadjusted period prevalence (%) 14.15 13.48 14.91
Median age at first event (years) 46.90 44.36 49.81

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: AUTOIMMUNE_NONTHYROID – Autoimmune diseases excluding thyroid diseases

GWS hits: 62

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