Suggestive for eosinophilic asthma

ASTHMA_EOSINOPHIL_SUGG

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

  • J10_ASTHMA
48366

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

2850

6. Filter based on genotype QC (FinnGen only)

2763

Control definitions (FinnGen only)

Control conditions not J10_ASTHMA

Extra metadata

First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 21151 9574 11468
Only index persons 19226 8895 10331
Unadjusted period prevalence (%)
Whole population 0.30 0.27 0.32
Only index persons 0.36 0.33 0.39
Median age at first event (years)
Whole population 51.33 50.38 52.09
Only index persons 50.40 49.51 51.17

-FinnGen-

Key figures

All Female Male
Number of individuals 2763 1341 1422
Unadjusted period prevalence (%) 0.69 0.58 0.78
Median age at first event (years) 50.17 47.65 52.55

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: ASTHMA_EOSINOPHIL_SUGG – Suggestive for eosinophilic asthma

GWS hits: 19

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