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Pulmonary eosinophilia, not elsewhere classified

DOID EFO Endpoint Browser PheWeb

J10_PULMEOS

eosinophilic pneumonia: An inflammatory lung disorder characterized by an increased number of eosinophils in the lungs. The majority of cases are idiopathic, without identifiable cause. In a minority of cases, medications, fungal infections, and environmental triggers have been implicated. It manifests as acute or chronic. Acute eosinophilic pneumonia is a severe and rapidly progressing pneumonia that may lead to respiratory failure requiring mechanical ventilation. Chronic eosinophilic pneumonia follows a slower course and manifests as fever, dyspnea, cough, and weight loss.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — J82
  • Hospital discharge: ICD-9 — 5183
  • Hospital discharge: ICD-8 — 51920
  • Cause of death: ICD-10 — J82
  • Cause of death: ICD-9 — 5183
  • Cause of death: ICD-8 — 51920

2 out of 7 registries used, show all original rules.

362

4. Check minimum number of events

None

362

5. Include endpoints

None

362

6. Filter based on genotype QC (FinnGen only)

349

Control definitions (FinnGen only)

Control exclude J10_INTERSTITIUM

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 J80-J84
Name in latin Eosinophilia pulmonum non alibi classificata

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3168 1780 1353
Only index persons 2462 1464 998
Unadjusted period prevalence (%)
Whole population 0.05 0.05 0.04
Only index persons 0.05 0.05 0.04
Median age at first event (years)
Whole population 59.21 58.03 60.60
Only index persons 56.56 55.95 57.46

-FinnGen-

Key figures

All Female Male
Number of individuals 349 193 156
Unadjusted period prevalence (%) 0.08 0.08 0.09
Median age at first event (years) 57.73 54.05 62.29

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: J10_PULMEOS – Pulmonary eosinophilia, not elsewhere classified

GWS hits: -

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