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Intestinal infectious diseases

DOID EFO Endpoint Browser PheWeb

AB1_INTESTINAL_INFECTIONS

amebiasis: A parasitic protozoa infectious disease that involves infection caused by the amoeba Entamoeba histolytica. Amebic invasion of the intestinal lining causes dysentery, colitis or diarrhea. The infection can also spread through the blood to the liver and, rarely, to the lungs, brain or other organs.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — A00-A09
  • Hospital discharge: ICD-9 — 00[1-9]
  • Hospital discharge: ICD-8 — 00[0-9]
  • Cause of death: ICD-10 — A00-A09
  • Cause of death: ICD-9 — 00[1-9]
  • Cause of death: ICD-8 — 00[0-9]

2 out of 7 registries used, show all original rules.

46727

4. Check minimum number of events

None

46727

5. Include endpoints

46727

6. Filter based on genotype QC (FinnGen only)

44966

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 671437 331887 335586
Only index persons 563226 278229 284997
Unadjusted period prevalence (%)
Whole population 9.41 9.51 9.38
Only index persons 10.56 10.23 10.88
Median age at first event (years)
Whole population 28.35 36.22 20.19
Only index persons 26.77 33.55 20.14

-FinnGen-

Key figures

All Female Male
Number of individuals 44966 24543 20423
Unadjusted period prevalence (%) 10.92 10.66 11.23
Median age at first event (years) 37.91 36.58 39.51

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: AB1_INTESTINAL_INFECTIONS – Intestinal infectious diseases

GWS hits: 3

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