Typhoid and paratyphoid fevers

AB1_TYPHOIDPARATHYPHOID

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 A01
  • Hospital discharge: ICD-9 002.
  • Hospital discharge: ICD-8 00[1-2]
  • Cause of death: ICD-10 A01
  • Cause of death: ICD-9 002.
  • Cause of death: ICD-8 00[1-2]

2 out of 7 registries used, show all original rules.

131

4. Check minimum number of events

None

131

5. Include endpoints

None

131

6. Filter based on genotype QC (FinnGen only)

125

Control definitions (FinnGen only)

Control exclude AB1_INTESTINAL_INFECTIONS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1560 772 765
Only index persons 1249 640 609
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.02
Only index persons 0.02 0.02 0.02
Median age at first event (years)
Whole population 34.76 36.42 32.62
Only index persons 29.08 30.04 28.08

-FinnGen-

Key figures

All Female Male
Number of individuals 125 75 50
Unadjusted period prevalence (%) 0.03 0.03 0.03
Median age at first event (years) 36.83 34.26 40.70

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: AB1_TYPHOIDPARATHYPHOID – Typhoid and paratyphoid fevers

GWS hits: -

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